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ENA - Extractable Nuclear Antigens
Connective tissue disease (CTD) is a common autoimmune disease. The connective tissues are structural portions of the body such as collagen and elastin which are essential to provide a framework or matrix for the body. In patients with CTD, it is common for collagen and elastin to become injured by inflammation. We have a useful part to play in the diagnosis and monitoring of patients with connective tissue disease. We have a CTD service which tests for systemic lupus erythematosus, rheumatoid arthiritis, scleroderma, polymyositis and dermatomyositis amongst many others. The CTD service provides the following test panel to aid in diagnosis:
Tests available are: Anti-Nuclear Antibody (ANA), Complement C3 and C4 (C34), Extractable Nuclear Antigen (ENA) and double stranded Deoxyribonucleic acid (DNA) antibody. Judicious use of these tests in conjunction with clinical history and examination can help in the diagnosis and monitoring of CTD.
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©SWBH NHS Trust 2018 |